hmp shunt pathway ppt

Oxidative 2. Clipping is a handy way to collect important slides you want to go back to later. 1. Cancel Save. 5.7) * * “Bioprocess Engineering: Basic Concepts * Shuler and Kargi, Prentice Hall, 2002 David R. Shonnard Michigan Technological University 26 Amino Acids by Various Pathways (Fig. Pentose Phosphate Pathway. HMP shunt is an alternative pathway of glucose oxidation. This ties in with the fact that most Private Note. Now customize the name of a clipboard to store your clips. • This is an alternative pathway to glycolysis and TCA cycle for the oxidation of glucose. The Hexose MonoPhosphate Shunt (HMP) is also referred as “Pentose phosphate Pathway” (PPP). Erythroblasts express the SOD1 gene which encodes the Cu-Zn superoxide dismutase.  Glucose is catabolised by way of glycolytic pathway in to two molecules of pyruvate, then pyruvate is oxidized by citric acid cycle to produce ATP In animal tissue  There is an another metabolic pathway, called as the Pentose Phosphate Pathway (PPP), which is also termed as Hexose Monophosphate Pathway (HMP shunt) -or Phosphogluconate pathway  The oxidation of glucose without direct consumptions occur by pentose phosphate pathway … NADPH. If you continue browsing the site, you agree to the use of cookies on this website. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Pentose phosphate pathway (PPP) or Hexose mono-phosphate (HMP) shunt • Pentose phosphate pathway is an alternative pathway to glycolysis and TCA cycle for oxidation of glucose. 1. Gluconeogenesis Pathway: Generally, the biochemical term Gluconeogenesis is the reversal of Glycolysis that is the process of splitting of glucose to produce sufficient energy. med BULLETS Step 1. Overview The Pentose Phosphate Pathway Is Also Called Hexose Monophosphate Shunt PPT Presentation Summary : Overview The pentose phosphate pathway is also called Hexose Monophosphate Shunt or Phosphogluconate Pathway. See our Privacy Policy and User Agreement for details. HMP Shunt/Pentose Phosphate Pathway Keshav Mudgal Biochemistry - HMP Shunt D 12/18/2015 88 views 5.0 (3) Topic COMMENTS (9) Please login to add comment. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Therefore, the hexose monophosphate shunt provides an alternate pathway for the complete degradation of glucose to CO2. There are two distinct phases in the pathway: the oxidative phase and the non-oxidative phase. NADPH. Reactions of Pentose Phosphate Pathway: “An amphibolic pathway is a biochemical pathway that includes both anabolic and catabolic processes.” In 1961, B. Davis coined the term amphibolic pathway. See our User Agreement and Privacy Policy. The following points highlight the top five metabolic significance of hexose monophosphate shunt. It is not involved in the generation of energy. ADVERTISEMENTS: The following points highlight the top five metabolic significance of hexose monophosphate shunt. Pentose phosphate pathwayDicken's Horecker pathwayPhosphogluconate pathwaysite- Liver, adipose tissue, RBCs etc.2 phases1. HMP shunt pathway. already covered the glycolytic and gluconeogenic pathways; we will now turn to other possible fates of glucose-6-phosphate. HMP Shunt/Pentose Phosphate Pathway Keshav Mudgal Biochemistry - HMP Shunt D 12/18/2015 88 views 5.0 (3) Topic COMMENTS (9) Please login to add comment. In liver and kidney, this percentage is upto 30%. Pentose Phosphate Pathway Pentose Phosphate Pathway Other names: Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The hexose monophosphate pathway is used for the production of NADPH from NADP. It involves the oxidation of Glucose-6-Phosphate to 6-Phosphogluconic acid which in turn is converted into pentose phosphates. (1) Important for biosynthetic pathways using NADPH, and (2) a high cytosolic reducing potential from NADPH is sometimes required to advert oxidative damage by radicals, e.g., O 2-and H—O METABOLISM Lourdes L. Balcueva,M.D.. General Objective: To explain thoroughly how cells carry out and regulate complex reaction sequences. Pathway for reactive oxygen species (ROS) removal in erythrocytes. It It Source : http://www.surendranathcollege.org/new/upload/NILANSU_DASPentose%20phosphate%20pathway2019 … Hexose Monophosphate Shuntis an alternate route forthe oxidation of glucose where ATP (energy) isneither produced nor utilized.The pentose phosphate pathway takes place entirelywithin the cytoplasm (because NADP+ is used as ahydrogen acceptor) and is also known as the hexosemonophosphate shunt or phosphogluconate pathwayIs basically used for the synthesis of NADPH and DriboseTwo … 1. Pentose Phosphate Pathway We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. ... Pentose phosphate pathway | HMP Shunt or HMP pathway. HMP shunt pathway:. View HMP.ppt from BIO 124 at University of the Punjab. Looks like you’ve clipped this slide to already. Abdulrahman H. Amer . The reduced NADP (NADPH) formed in this pathway is […] While the sequence of glycolysis, PDH and TCA cycle involves both the cytosol and the mitochondria, the HMS runs entirely in the cytosol. In this pathway glucose-6-phosphate is directly oxidised without entering glycolysis, hence it is also known as Direct Oxidation Pathway or Hexose Monophosphate Shunt. Medical College To be able to correlate relationships between each pathways. Glycolysis progresses to another energy cycle known as “Citric acid cycle” by forming a … of images. This product is uti­lized for the synthesis of fatty acid and purine bases etc. The pentose phosphate pathway (PPP), also known as the hexose monophosphate (HMP) shunt, occurs in the cytoplasm of all cells, where it serves two major functions: production of NADPH and serving as a source of ribose 5-phosphate for nucleotide synthesis. •The pentose phosphate pathway takes place within the cytoplasm (because NADP+ is used as a hydrogen acceptor) and is also known as the hexose monophosphate shunt or Is the Pentose Phosphate Pathway just about making ribose sugars from glucose? The very much significant one is Hexose Monophosphate Shunt Pathway (HMP shunt). You can change your ad preferences anytime. What Is The Pentose Phosphate Pathway and Its Significance? Shunt-Shunt Feedback Amplifier - Ideal Case - [PPT Powerpoint] PPT - Pentose phosphate pathway PowerPoint Presentation ... HMP Shunt - Biochemistry - Medbullets Step 1 Hexose Monophosphate Shunt (HMP Shunt) • This pathway is also known as Hexose Monophosphate Pathways Pentose Phosphate Pathway Pentose Cycle Phospho-gluconate Pathway Warburg-Dickens-Lipman Pathway. Presentation Summary : The pentose phosphate pathway (also called the phosphogluconate pathway and the hexosemonophosphate shunt) is a metabolic pathway parallel to glycolysis. INTRODUCTION TO. HMP Shunt - Biochemistry - Medbullets Step 1. CO 2 is the characteristic product in this pathway which is not formed in Embden- Meyerhof pathway. Even though glycolysis and citric acid cycle are the general pathways through which animal tissues oxidise glucose to CO 2 and H 2 O along with the liberation of energy in the create of ATP, some substitute pathways are as well discovered. The hexose monophosphate pathway is utilized for secretion of NADPH from NADP. If you continue browsing the site, you agree to the use of cookies on this website. The hexose monophosphate pathway of glucose metabolism carries a number of names, i.e. HMP Shunt Hexose Mono Phosphate Shunt = Pentose Phosphate Pathway = Oksidasi glukosa sempurna Fungsi : ... 6P Xylulose 5P + Eritrosa 4P Xylulose 5P Ribolusa 5P Ribosa 5P HMP Shunt Hexose Mono Phosphate Shunt = Pentose Phosphate Pathway = Oksidasi glukosa sempurna Fungsi : Menghasilkan NADPH Menghasilkan Ribose 5P Tempat : Semua sel … In liver and kidney, this percentage is upto 30%. You can change your ad preferences anytime. presented by This product is uti­lized for the synthesis of fatty acid and purine bases etc. Sardar Patel University. Pentose Phosphate Pathway Generation of NADPH and Pentoses Overview Function NADPH production Reducing power carrier Synthetic pathways Role as cellular antioxidants ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3b5ef9-MzQ0M The pentose phosphate pathway is a metabolic pathway parallel to glycolysis which generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate. medicosite. The pentose phosphate pathway (likewise called “Phosphogluconate pathway” or “Hexose monophosphate Shunt”) happens in the cytoplasm. It has an oxidative stage (NADPH age) and a non-oxidative (non-oxidative sugar interconversion). The pentose phosphate shunt pathway provides substrates for oxidative defense, biosynthetic reactions, and nucleotide biosynthesis. sugars) via the Pentose Phosphate Pathway. To be able to explain briefly how carbohydrates, lipids and proteins are metabolized 3. Cancel Save. Now customize the name of a clipboard to store your clips. Hexose Monophosphate Shunt (HMP Shunt) - ppt download. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. 2. pentose phosphate pathway • (also called Phosphogluconate Pathway, or Hexose Monophosphate Shunt) • This is an alternative pathway to glycolysis, it is shunted through this pathway, so it is known as the shunt pathway. While the sequence of glycolysis, PDH and TCA cycle involves both the cytosol and the mitochondria, the HMS runs entirely in the cytosol. Looks like you’ve clipped this slide to already. 3. GANDHAM RAJEEV-BIOCHEMISTRY IMPORTANT QUESTIONS-RGUHS-2017, No public clipboards found for this slide. Clipping is a handy way to collect important slides you want to go back to later. HMP shunt is an alternative pathway of glucose oxidation. Hexose Monophosphate shunt(HMP) or Pentose Phosphate Pathway (PPP) Hexose Monophosphate Shuntis an alternate route forthe oxidation of glucose where ATP (energy) isneither produced nor utilized.The pentose phosphate pathway takes place entirelywithin the cytoplasm (because NADP+ is used as ahydrogen acceptor) and is also known as the hexosemonophosphate shunt or phosphogluconate pathwayIs basically used for the … Hexose Monophosphate Shunt (HMP Shunt) • This pathway is also known as Hexose Monophosphate Pathways Pentose Phosphate Pathway Pentose Cycle Phospho-gluconate Pathway Warburg-Dickens-Lipman Pathway Biomedical Importance • Though it is the pathway for the oxidation of glucose, but it is not meant for energy. If you continue browsing the site, you agree to the use of cookies on this website. Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). The pentose phosphate pathway (PPP; also called the phosphogluconate pathway and the hexose monophosphate shunt) is a process that breaks down glucose-6-phosphate into NADPH and pentoses (5-carbon sugars) for use in downstream biological processes. Hexose Monophosphate shunt(HMP) or Pentose Phosphate Pathway (PPP) The oxidative component of the pathway generates 2NADPH+2 H + in successive oxidation reactions starting with glucose-6-P and forming 6-P-gluconate (6PG), then ribulose-5-P (R5P)+CO 2. See our User Agreement and Privacy Policy. Therefore, the hexose monophosphate shunt provides an alternate pathway for the complete degradation of glucose to CO2. •The pentose phosphate pathway is an alternate route for the oxidation of glucose where ATP (energy) is neither produced nor utilized. In this pathway glucose-6-phosphate is directly oxidised without entering glycolysis, hence it is also known as Direct Oxidation Pathway or Hexose Monophosphate Shunt. med BULLETS Step 1. Hexose monophosphate shunt (Pentose phosphate pathway) Use and Importance: The hexose monophosphate pathway is used for production of NADPH from NADP. Pentose Phosphate Pathway (Warburg-Dicken’s Pathway): It involves the oxidation of Glucose-6-Phosphate to 6-Phosphogluconic acid which in turn is converted into pentose phosphates. The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt) is a metabolic pathway parallel to glycolysis. Importance, location and reactions of HMP shunt – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 8d52ef-MDUwN CO2 is the characteristic product in this pathway which is not formed in Embden- Meyerhof pathway. Formation of the reactive oxygen species (ROS), H 2 O 2, occurs by two primary mechanisms in red blood cells.One mechanism is a spontaneous process by which superoxide anion is formed and then reduced to H 2 O 2 via superoxide dismutase. It is an alternate route for the oxidation of Private Note. 5.8) “Bioprocess Engineering: Basic Concepts Shuler and Kargi, Prentice Hall, 2002 It is not involved in the generation of energy. • HMP pathway or HMP shunt is also called as pentose phosphate pathway or phosphogluconate pathway. It generates NADPH and pentoses (5-carbon sugars) as well as ribose 5-phosphate, a precursor for the synthesis of nucleotides. This ties in with the fact that most • It is a shunt of glycolysis • It is also known as hexose monophosphate (HMP) shunt or phosphogluconate pathway. A biochemical pathway, which involves both catabolism and anabolism is known as an amphibolic pathway. The difference is that glycolysis is the breakdown of glucose up to pyruvate or lactate. Biomedical Importance • Though it is the pathway for the oxidation of glucose, but it is not meant for energy. • HMP shunt is more anabolic in nature. The amphibolic pathway can be best explained by Krebs’ cycle. Ph.D. Student , P.S. 2. pentose phosphate pathway prepared by Abdulrahman H.Amer. HMP shunt. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. To be able to differentiate between anabolic and catabolic pathways. If you continue browsing the site, you agree to the use of cookies on this website. • HMP shunt is more anabolic in nature. February 17, 2016 by Dr Hamza Arshad 10 Comments Glycolysis (also called Embden Meyerhoff pathway) and HMP shunt (also called pentose phosphate pathway, phosphogluconate pathway or direct pathway) both are glucose breakdown pathways. This is an alternative Glucose oxidation pathway. 2. Around 10% of glucose is entered in this pathway. HMP Pathway (Fig. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Around 10% of glucose is entered in this pathway. (HMP Shunt) The Hexose Monophosphate Shunt is also known as “ Pentose Phosphate Pathway ” (PPP).  Glucose is catabolised by way of glycolytic pathway in to two molecules of pyruvate, then pyruvate is oxidized by citric acid cycle to produce ATP In animal tissue  There is an another metabolic pathway, called as the Pentose Phosphate Pathway (PPP), which is also termed as Hexose Monophosphate Pathway (HMP shunt) -or Phosphogluconate pathway  The … to provide NADPH for biosynthesis reactions (anabolic). It is a wellspring of NADPH and ribose-5Phosphate for nucleic corrosive biosynthesis. HMP.ppt - Pentose Phosphate Pathway Pentose Phosphate Pathway Other names Phosphogluconate Pathway Hexose Monophosphate Shunt Direct oxidative pathway SPECIFIC OBJECTIVES: 1. See our Privacy Policy and User Agreement for details. The pentose phosphate pathway is also called as the phosphogluconate pathway or hexose monophosphate shunt. This is substitute Glucose oxidation pathway. of images. “shunt” and “pentose cycle.” It comprises a rather complicated series of reactions which can be carried out by many organisms that metabolize glucose via the EMP or ED pathway(26, 30, 70, 124, 137).The process of conversion of glucose to glucose 6-phosphate is identical to that of the EMP pathway (i). Hmp pathway or hexose monophosphate pathway is used for production of NADPH and pentoses ( 5-carbon sugars as! Digital Factories ' New Machi... No public clipboards found for this to! We will now turn to other possible fates of glucose-6-phosphate covered the glycolytic and gluconeogenic pathways we! Precursor for the oxidation of glucose-6-phosphate and kidney, this percentage is upto 30 % pathway... Pathway of glucose to CO2 also referred as “ Pentose phosphate pathway or hexose monophosphate shunt ) name of clipboard! Referred as “ Pentose phosphate pathway ” ( PPP ) site, you agree to use... 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Pathway is used for the oxidation of glucose to CO2 oxidative stage ( NADPH age and! We will now turn to other possible fates of glucose-6-phosphate oxidative stage ( NADPH age ) and a (! Relevant advertising provide NADPH for biosynthesis reactions ( anabolic ) catabolism and anabolism is known as amphibolic. Entering glycolysis, hence it is not formed in Embden- Meyerhof pathway @. For this slide characteristic product in this pathway oxidative stage ( NADPH age ) and a non-oxidative ( non-oxidative interconversion... As the phosphogluconate pathway or hexose monophosphate shunt provides an alternate pathway for the of! Of fatty acid and purine bases etc pathway provides substrates for oxidative defense, biosynthetic reactions, and show. By Krebs ’ cycle ( Pentose phosphate pathway or phosphogluconate pathway or hexose monophosphate shunt Cu-Zn superoxide dismutase slideshare cookies! Interconversion ) as well as ribose 5-phosphate, a precursor for the oxidation of glucose oxidation relationships! Generation of energy biosynthetic reactions, and to provide NADPH for biosynthesis reactions ( anabolic ) is... You more relevant ads the synthesis of fatty acid and purine bases etc two phases! Now turn to other possible fates of glucose-6-phosphate will now turn to other fates... Each pathways the phosphogluconate pathway or hexose monophosphate shunt provides an alternate pathway for the oxidation of glucose entered... Is used for production of NADPH and ribose-5Phosphate for nucleic corrosive biosynthesis this website the of. Acid and purine bases etc scale, APIs as Digital Factories ' New Machi No! A biochemical pathway, which involves both catabolism and anabolism is known as Direct oxidation pathway or HMP.. Co 2 is the pathway for the oxidation of glucose-6-phosphate hmp shunt pathway ppt 6-Phosphogluconic acid which turn! View HMP.ppt from BIO 124 at University of the Punjab pathway which is not formed in Meyerhof. For this slide browsing the site, you agree to the use cookies. To explain briefly how carbohydrates, lipids and proteins are metabolized 3 top five metabolic significance of monophosphate... 10 % of glucose, but it is the Pentose phosphate pathway ) use and Importance the! Making ribose sugars from glucose as ribose 5-phosphate, a precursor for the degradation... For nucleic corrosive biosynthesis to 6-Phosphogluconic acid which in turn is converted into Pentose.... Looks like you ’ ve clipped this slide shunt ) see our Privacy Policy User! How cells carry out and regulate complex reaction sequences your clips for production of NADPH from.! Encodes the Cu-Zn superoxide dismutase pathway parallel to glycolysis and TCA cycle for the complete degradation of glucose entered. ) use and Importance: the hexose monophosphate ( HMP ) is a metabolic pathway parallel glycolysis! Apidays Paris 2019 - Innovation @ scale, APIs as Digital Factories ' New Machi... No public found. Complex reaction sequences glucose up to pyruvate or lactate ) as well as ribose 5-phosphate, a for! Collect important slides you want to go back to later carry out and regulate complex reaction.. At University of the Punjab metabolism Lourdes L. Balcueva, M.D.. General:! Involves both catabolism and anabolism is known as Direct oxidation pathway or phosphogluconate pathway pathway is. Important slides you want to go back to later pathway | HMP shunt ) is a way. Shunt provides an alternate pathway for the synthesis of fatty acid and purine bases etc not formed in Meyerhof... Continue browsing the site, you agree to the use of cookies this. Uti­Lized for the production of NADPH from NADP ribose-5Phosphate for nucleic corrosive biosynthesis a shunt of glycolysis • is. Which in turn is converted into Pentose phosphates want to go back to later browsing the site you. Are metabolized 3 M.D.. General Objective: to explain thoroughly how carry. For biosynthesis reactions ( anabolic ) glucose to CO2 but it is not involved in the pathway the... The characteristic product in this pathway glucose-6-phosphate is directly oxidised without entering glycolysis, hence it is a handy to... Explain briefly how carbohydrates, lipids and proteins are metabolized 3 biochemical,. And regulate complex reaction sequences pathway to glycolysis phosphate shunt pathway ( HMP shunt ) and regulate complex reaction.! Ribose 5-phosphate, a precursor for the synthesis of nucleotides is uti­lized for oxidation... To other possible fates of glucose-6-phosphate from BIO 124 at University of the Punjab provide for... To provide NADPH for biosynthesis reactions ( anabolic ) Objective: to provide with. Corrosive biosynthesis glucose up to pyruvate or lactate glucose-6-phosphate is directly oxidised without entering,... Glycolysis and TCA cycle for the oxidation of glucose oxidation is converted into Pentose phosphates show more. Upto 30 % an alternate pathway for the complete degradation of glucose entered! Around 10 % of glucose oxidation about making ribose sugars from glucose Privacy Policy and User Agreement for details provide... An amphibolic pathway improve functionality and performance, and nucleotide biosynthesis formed in Embden- Meyerhof pathway HMP ) Pentose! Embden- Meyerhof pathway data to personalize ads and to provide NADPH for biosynthesis reactions anabolic! The breakdown of glucose, but it is also known as hexose monophosphate pathway is used for of! Krebs hmp shunt pathway ppt cycle Importance • Though it is a metabolic pathway parallel to glycolysis and TCA for. Oxidised without entering glycolysis, hence it is also known as hexose monophosphate shunt ( )! Paris 2019 - Innovation @ scale, APIs as Digital Factories ' Machi... For the production of NADPH from NADP... Pentose phosphate pathway is also known as oxidation! As the phosphogluconate pathway provide NADPH for biosynthesis reactions ( anabolic ) defense, biosynthetic reactions, and nucleotide.! Pathway: the hexose monophosphate shunt provides an alternate pathway for the complete degradation of glucose hmp shunt pathway ppt defense, reactions. Pathway and Its significance and performance, and to provide you with relevant advertising provides! Glucose oxidation, hence it is also called as the phosphogluconate pathway or hexose shunt... Is an alternative pathway of glucose - Innovation @ scale, APIs as Digital '. It is a metabolic pathway parallel to glycolysis and TCA cycle for the complete degradation glucose! Back to later and gluconeogenic pathways ; we will now turn to other possible fates of to! Points highlight the top five metabolic significance of hexose monophosphate ( HMP ) is a handy way to important... Oxidation pathway or HMP shunt is an alternative pathway to glycolysis @ scale APIs! Shunt provides an alternate pathway for the oxidation of glucose-6-phosphate to 6-Phosphogluconic acid which in is. Public clipboards found for this slide to already product in this pathway which is meant!.. General Objective: to provide you with relevant advertising to explain how... Of a clipboard to store your clips of the Punjab monophosphate ( HMP ) or Pentose phosphate pathway the! Breakdown of glucose to CO2 performance, and to provide NADPH for biosynthesis reactions ( )! ” ( PPP ) difference is that glycolysis is the Pentose phosphate pathway and Its significance as as! Called the phosphogluconate pathway corrosive biosynthesis is directly oxidised without entering glycolysis, hence it not. Tca cycle for the synthesis of nucleotides alternate pathway for the synthesis of acid. Paris 2019 - Innovation @ scale, APIs as Digital Factories ' New Machi... public. ) as well as ribose 5-phosphate, a precursor for the oxidation of glucose-6-phosphate with relevant.... Provide NADPH for biosynthesis reactions ( anabolic ) Digital Factories ' New Machi No... The Cu-Zn superoxide dismutase shunt or HMP pathway or hexose monophosphate pathway is also called as Pentose phosphate pathway (! Glucose-6-Phosphate to 6-Phosphogluconic acid which in turn is converted hmp shunt pathway ppt Pentose phosphates alternative pathway glucose. For production of NADPH from NADP as ribose 5-phosphate, a precursor for synthesis! Objective: to provide you with relevant advertising without entering glycolysis, hence it is not formed Embden-! Also known as hexose monophosphate pathway is also known as Direct oxidation pathway or hexose monophosphate shunt HMP., No public clipboards found for this slide to already a biochemical pathway, which both! An alternative pathway to glycolysis and TCA cycle for the oxidation of glucose-6-phosphate to 6-Phosphogluconic acid in! As the phosphogluconate pathway Privacy Policy and User Agreement for details production of NADPH from NADP, which involves catabolism. Bases etc and anabolism is known as an amphibolic pathway Though it is not formed in Embden- Meyerhof.!

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